第54回ARIHHP・IIIS共催セミナー
第54回ARIHHPセミナー (IIIS(国際統合睡眠医科学研究機構)との共催セミナー)
日時
2019年9月18日(火)9:00-10:00
会場︓ 筑波大学 医学系エリア 睡眠医科学研究棟 1F 講堂
タイトル
Cold-induced thermogenesis: a cold shoulder for obesity treatment ?
講師
Dr. Kong Y. Chen
Metabolic Clinical Research Unit, NIH Clinical Center / The National Institute of Diabetes and Digestive and Kidney Diseases
概要
Human energy metabolism is highly regulated and adaptive to environmental changes. It has been long appreciated that cold exposures can increase energy expenditure (cold-induced thermogenesis or CIT). The recent rediscovery of brown adipose tissue in adult humans have spurred interests in this potential mechanism to increase energy expenditure to combat obesity. We quantified the CIT response to different environmental temperatures in a whole-room indirect calorimeter, determined the capacity of CIT, lower critical temperatures, muscle shivering activities, and explored factors potentially contributing to the differences in thermal physiology between lean vs. obese healthy young men.
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